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Consumer Section

Stroke

In 1980 the U.S. Food and Drug Association approved the use of aspirin to help reduce the risk of stroke after a transient ischemic attack (TIA) - a mini stroke. (For the warning signs of TIA click here.)

The FDA's followed a Canadian study that discovered that aspirin reduced the risk of subsequent TIA by 19 percent and the risk of a second stroke by 31 percent. The study concluded that aspirin was effective in reducing the incidence of threatened stroke.

The most common form of stroke is caused when a blood vessel that supplies the brain with oxygen and nutrients becomes blocked by a blood clot.

There are two types of this clot-induced stroke:

A cerebral thrombosis occurs when a blood clot forms around a blood-vessel deposit (known as a thrombus) in a vessel that serves the brain. When the clot grows too large, it blocks the flow of oxygen and nutrients to the brain, inducing a stroke. This type of stroke is the most common and often occurs in arteries damaged by atherosclerosis.

A cerebral embolism occurs when a blood clot forms in the body (known as a embolus), usually in the heart, and travels through the blood stream to the brain. Once in the brain, the blood clot will lodge itself in a smaller blood vessel and block the flow of blood.

Aspirin plays a key role in helping lessen the chances of these two types of stroke from occurring by blocking platelets from producing the prostaglandin thromboxane, which is critical in the clotting action of blood.

 


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